Limitations of next-generation genome sequence assembly : Nature Methods : Nature Publishing Group
See on Scoop.it – Virology and Bioinformatics from Virology.ca
“High-throughput sequencing technologies promise to transform the fields of genetics and comparative biology by delivering tens of thousands of genomes in the near future. Although it is feasible to construct de novo genome assemblies in a few months, there has been relatively little attention to what is lost by sole application of short sequence reads……”
See on www.nature.com