Universal Pacemaker of Genome #Evolution
See on Scoop.it – Virology and Bioinformatics from Virology.ca
Sagi Snir, Yuri I. Wolf, Eugene V. Koonin
A fundamental observation of comparative genomics is that the distribution of evolution rates across the complete sets of orthologous genes in pairs of related genomes remains virtually unchanged throughout the evolution of life, from bacteria to mammals. The most straightforward explanation for the conservation of this distribution appears to be that the relative evolution rates of all genes remain nearly constant, or in other words, that evolutionary rates of different genes are strongly correlated within each evolving genome.
See on www.ploscompbiol.org