Vaccination evokes gender-dependent protection against tularemia infection in C57BL/6Tac mice
Highlights
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Gender bias is demonstrated in vaccination and protection against Ft challenge.
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Following vaccination, female mice are better protected than male mice.
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Ab, cytokine, and bacterial clearance studies are consistent with the above.
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Gender bias is apparent with both Ft LVS and highly virulent Ft SchuS4.
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Gender must be considered to accurately evaluate vaccine efficacy.
Vaccination evokes gender-dependent protection against tularemia infection in C57BL/6Tac mice
Source: Virology News
