Synima: a Synteny imaging tool for annotated genome assemblies – BMC Bioinformatics

BackgroundOrtholog prediction and synteny visualization across whole genomes are valuable methods for detecting and representing a range of evolutionary processes such as genome expansion, chromosomal rearrangement, and chromosomal translocation. Few standalone methods are currently available to visualize synteny across any number of annotated genomes.ResultsHere, I present a Synteny Imaging tool (Synima) written in Perl, which uses the graphical features of R. Synima takes orthologues computed from reciprocal best BLAST hits or OrthoMCL, and DAGchainer, and outputs an overview of genome-wide synteny in PDF. Each of these programs are included with the Synima package, and a pipeline for their use. Synima has a range of graphical parameters including size, colours, order, and labels, which are specified in a config file generated by the first run of Synima – and can be subsequently edited. Synima runs quickly on a command line to generate informative and publication quality figures. Synima is open source and freely available from https://github.com/rhysf/Synima under the MIT License.ConclusionsSynima should be a valuable tool for visualizing synteny between two or more annotated genome assemblies.See it on Scoop.it, via Viruses, Immunology & Bioinformatics from Virology.uvic.ca
Synima: a Synteny imaging tool for annotated genome assemblies – BMC Bioinformatics
Source: Viral Bioinformatics