Understanding the drivers of MHC restriction of T cell receptors

Review Article Jamie Rossjohn and colleagues review the structural and functional data that provide insight into the MHC restriction of T cell receptors. They discuss the non-mutually exclusive contributions of intrinsic germline-encoded motifs and developmental selection to MHC restriction.See it on Scoop.it, via Viruses, Immunology & Bioinformatics from Virology.uvic.ca
Understanding the drivers of MHC restriction of T cell receptors
Source: Viral Bioinformatics

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