HLA-C downregulation by HIV-1 adapts to host HLA genotype
Author summary HLA-C is a member of the major histocompatibility complex class-I (MHC-I) family of molecules which are integral to many responses of innate and adaptive immunity. HIV-1 can downregulate the expression level of HLA-C on infected cells, using the viral protein Vpu, but the magnitude…See it on Scoop.it, via Viruses, Immunology & Bioinformatics from Virology.uvic.ca
HLA-C downregulation by HIV-1 adapts to host HLA genotype
Source: Viral Bioinformatics
