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The hepatitis B virus (HBV) infects hepatocytes, which are the main cell type composing a human liver. However, the liver is enriched with immune cells, particularly innate cells (e.g., myeloid cells, natural killer and...

Human immunodeficiency virus type 1 (HIV-1) Tat is a virus-encoded trans-activator that plays a central role in viral transcription. We used our recently developed parallel analysis of in vitro translated open reading frames (ORFs)...

Several cellular functions such as apoptosis, cellular proliferation, inflammation, and immune regulation involve the tumor necrosis factor-α (TNF)/TNF receptor (TNFR) pathway. Human immunodeficiency virus 1 (HIV-1) interacts with the TNF/TNFR pathway. The activation of...

Oncolytic viruses are cancer therapeutics with promising outcomes in pre-clinical and clinical settings. Animal viruses have the possibility to avoid pre-existing immunity in humans, while being safe and immunostimulatory. We isolated an avian orthoreovirus...

The 17D line of yellow fever virus vaccines is among the most effective vaccines ever created. The humoral and cellular immunity elicited by 17D has been well characterized in humans. Neutralizing antibodies have long...

Intravenous viruses used to target deadly bacterium; dramatic case suggests potential alternative to failing antibioticsSee it on Scoop.it, via Viruses and Bioinformatics from Virology.uvic.ca Phage Therapy Saves Patient from Drug-Resistant Microbes | GEN Genetic...

Viruses are a major focus of current research efforts because of their detrimental impact on humanity and their ubiquity within the environment. Bacteriophages have long been used to study host‐viruSee it on Scoop.it, via...

See it on Scoop.it, via Viruses and Bioinformatics from Virology.uvic.ca Defective HIV proviruses hinder immune system response and cure Source: Viral Bioinformatics

See it on Scoop.it, via Viruses and Bioinformatics from Virology.uvic.ca Influenza: More efficient, more protective vaccinations Source: Viral Bioinformatics

Large-size data on type-specific HPV prevalence in Southwest China are required to estimate the cervical cancer burden in the country and to prepare for HPV-based cervical screening program and further HPV vaccination of China....