Category: Uncategorized

Evolution and Vaccination of Influenza Virus

In this study, we present an application paradigm in which an unsupervised machine learning approach is applied to the high-dimensional influenza genetic sequences to investigate whether vaccine is a driving force to the evolution...

Pathways to zoonotic spillover

Zoonotic spillover, which is the transmission of a pathogen from a vertebrate animal to a human, presents a global public health burden but is a poorly understood phenomenon. Zoonotic spillover requires several factors to...

Viral infection: Packing to leave

An essential feature of the life cycle of hepatitis B virus (HBV) is the packaging of the viral RNA pre-genome (pgRNA) into virions. It has been hypothesized that pgRNA is specifically packaged into viral...

Diversity of large DNA viruses of invertebrates

In this review we provide an overview of the diversity of large DNA viruses known to be pathogenic for invertebrates. We present their taxonomical classification and describe the evolutionary relationships among various groups of...