PLOS Computational Biology: Estimation of Vaccine Efficacy and Critical Vaccination Coverage in Partially Observed Outbreaks

See on Scoop.itVirology and Bioinformatics from Virology.ca

Classical approaches to estimate vaccine efficacy are based on the assumption that a person’s risk of infection does not depend on the infection status of others. This assumption is untenable for infectious disease data where such dependencies abound. We present a novel approach to estimating vaccine efficacy in a Bayesian framework using disease transmission models.

See on www.ploscompbiol.org

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