Isaac: Ultra-fast whole genome secondary analysis on Illumina sequencing platforms.
See on Scoop.it – Virology and Bioinformatics from Virology.ca
An ultrafast DNA sequence aligner (Isaac Genome Alignment Software) that takes advantage of high memory hardware (>48GB) and variant caller (Isaac Variant Caller) have been developed. We demonstrate that our combined pipeline (Isaac) is 4-5 times faster than BWA+GATK on equivalent hardware, with comparable accuracy as measured by trio conflict rates and sensitivity.
See on postolog.com
