BMC Bioinformatics | Abstract | SeqSIMLA: a sequence and phenotype simulation tool for complex disease studies
See on Scoop.it – Virology and Bioinformatics from Virology.ca
Association studies based on next-generation sequencing (NGS) technology have become popular, and statistical association tests for NGS data have been developed rapidly. A flexible tool for simulating sequence data in either unrelated case–control or family samples with different disease and quantitative trait models would be useful for evaluating the statistical power for planning a study design and for comparing power among statistical methods based on NGS data.
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