The dangers of default parameters in bioinformatics: lessons from Bowtie and TopHat

Most bioinformatics tools are equipped with a vast array of command-line options which let the user configure the inputs, outputs, and performance of the software. You may not wish to explore every possible option when using a particular piece of software, but you should always try to have a look at the manual. 

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See on Scoop.itVirology and Bioinformatics from Virology.ca

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